As Cuba's second largest city, Santiago de Cuba is poised to be a popular stop on voyages to the island nation. Cruising into port, you can't miss the site of the Sierra Maestra mountains on Cuba's south coast and the imposing El Morro at the narrow entrance to its bay. Known as the birthplace of the revolución and a hotbed for Afro-Cuban culture, visitors won't be disappointed in the vibrant history, music, art, and architecture.